![]() ![]() At lower doses, users report alcohol-like disinhibition and relaxation effects. It is known for producing relatively "pure" dissociation, without as much stimulation and mania as PCP or MXE.Īdditionally, the effects of ketamine are highly dose-dependent. The effects are similar to PCP and DXM but with a shorter duration and a rapid onset. Subjective effects include motor control loss, pain relief, internal hallucinations, memory suppression, conceptual thinking, immersion enhancement, euphoria, and depersonalization / dissociation. Today, it is associated in popular culture with the nightclub and rave scenes. Recreational use was first reported amongst medicinal chemists in the United States in 1967, and became more widespread in Europe in the 1990s, where it gained popularity as an adulterant in ecstasy tablets. Recently, it has received significant clinical research following the discovery that it can rapidly relieve treatment-resistant depression and suicidal ideation. ![]() It is now widely used in human and veterinary medicine, typically in surgical and intensive care settings. The mechanism of action is not fully known, although blocking of the NMDA glutamate receptor is thought to be involved.ĭeveloped in 1963 by Parke-Davis Laboratories, it was originally intended as a replacement for the surgical anesthetic phencyclidine (PCP). It is perhaps the best-known and archetypal member of the dissociatives, a diverse group which includes PCP, methoxetamine, DXM, and nitrous oxide. Ketamine (also known as Ket, K, Special K, vitamin K, Kitty, and others) is a classical dissociative substance of the arylcyclohexylamine class. It is not a recommendation and should be verified with other sources for accuracy. See responsible use section.ĭISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. (RS)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone ![]() Ketamine, K, Ket, Kitty, Special K, Cat Tranquilizer, Ketaset, Ketalar, Ketanest, Vitamin K, Purple, Jet ![]()
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